Pixel Club: DT-MRI Guided Focused Ultrasound

Hagai Tzafrir (CS, Technion)
Thursday, 6.4.2017, 13:30
Taub 201

We present an analysis method to improve treatment procedures for a set of neurological pathologies, specifically essential tremor disorder. By combining anatomical and pathological knowledge with modern geometric analysis tools of MRI, an efficient focused ultrasound treatment procedure is introduced. As a first step, we apply statistical geometric tools for in-vivo analysis of the brain. The brain's connectivity structure is interpreted based on diffusion tensor-MRI. Next, mapping the brain structure onto a representative dictionary template allows us to locate regions of functional interest. Finally, applying efficient statistical geometric tools to the DT-MRI, the brain's connectivity structure can be estimated and used to pinpoint the location to be treated with the focused ultrasound (FUS). The potential of personalized medical treatment is demonstrated by the suggested procedure which is validated on a set of successful FUS ablation operations.

*Supervised by Professor Ron Kimmel

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